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產(chǎn)品中心抗體Polyclonal AntibodyK106492PAnti-CRHR2 Polyclonal Antibody
產(chǎn)品型號：K106492P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：1124
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產(chǎn)品分類
Anti-CRHR2 Polyclonal Antibody
| 英文名稱 | Anti-CRHR2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | CRF2R;CRH2R;CRF-RB;CRF2;CRFR2;HM-CRF |
| 應(yīng)用 | WB IHC |
| 稀釋比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 45kDa |
| Gene ID | 1395 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human CRHR2 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human CRHR2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q13324 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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