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產(chǎn)品中心抗體Polyclonal AntibodyK106486PAnti-SIRT1 Polyclonal Antibody
產(chǎn)品型號：K106486P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：1028
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產(chǎn)品分類
Anti-SIRT1 Polyclonal Antibody
| 英文名稱 | Anti-SIRT1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | SIR2;SIR2alpha;SIR2L1;SIR2-like protein 1;Hsir2 |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 130kDa |
| Gene ID | 23411 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human SIRT1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human SIRT1 |
| Subcellular Locations | Cytoplasm Nucleus Mitochondrion |
| Swiss Prot | Q96EB6 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |
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