Spermidine（胺鹽）

說明：抑制神經(jīng)元氧化一氮合成酶(nNOS)活性；能與DNA結(jié)合沉淀DNA，被用于與蛋白質(zhì)相結(jié)合的DNA的純化；刺激T4多聚核苷酸激酶的活性。

別名： N-(3-氨基丙基)-1 ， 4-二氨基丁烷；N-(3-氨基丙基)-1， 4-丁二胺；
1,8-Diamino-4-azaoctane；N-(3-Aminopropyl)-1,4-diaminobutane

分子式：C7H19N3 分子量：145.25

C A S ＃：124-20-9

外觀：白色固體或淺黃色液體

特性：溶解性：溶于水

R：34 S：26-36/37/39-45

儲(chǔ)存條件： 2-8℃

亞精胺(精脒)結(jié)構(gòu)式：

Spermidine
Storage Temperature 2-8 °C
Product Description
Molecular Formula: C 7 H 19 N 3
Molecular Weight: 145.2
CAS Number: 124-20-9
Melting Point: 23-25 °C
Density: 0.925 g/ml
Refractive Index: 1.4790 (20 °C)
This product is suitable for molecular biology applications. DNase, RNase, or protease activities were not detected.
Spermidine is biogenic polyamine formed from putrescine, a precursor of spermine. It was first detected in human sperm, but occurs widely in nature.
It is essential in both normal and neoplastic tissue growth.

1Spermidine has a role in cell growth processes 

2 and the formation and interconversion of spermidine in mammalian cells has been reported.

3It has been studied in the regulation of tRNA methyltransferase activity

4and stimulates T4 polynucleotide kinase activity.

5 Precautions and Disclaimer
For Laboratory Use Only. Not for drug, household or other uses.
Preparation Instructions Spermidine is soluble in water (50 mg/ml), ethanol,
and ether.

6Storage/Stability Spermidine is very hygroscopic and air sensitive.

A solution can be formed for storage by dissolving 1.45 g in 10 ml of water and then sterilizing with a 0.22 μm filter. Store this solution as single-use aliquots at ?20 °C for no more than one month.

7 Spermidine free base should be sterile-filtered and not autoclaved, if a sterile solution is necessary. 

References
1. The Index, 11th ed., Entry# 8698.

2. Janne, J., et al., Polyamines in Rapid Growth and Cancer. Biochim. Biophys. Acta, 473(3-4), 241-293 (1978).

3. Porter, C. W., and Bergeron, R. J., Spermidine Requirement for Cell Proliferation in Eukaryotic
Cells: Structural Specificity and Quantitation.
Science, 219(4588), 1083-1085 (1983).

4. Pegg, A. E., et al., Formation and Interconversion of Putrescine and Spermidine in Mammalian Cells. Adv. Enzyme Regul., 19, 427-451 (1980).

5. Mach, M., et al., Regulation of tRNA Methyltransferase Activities by Spermidine and Putrescine. Inhibition of Polyamine Synthesis and tRNA Methylation by Alpha-methylornithine or 1,3-diaminopropan-2-ol in Dictyosium. Biochem. J.,
202(1), 153-162 (1982).

6. Molecular Cloning: A Laboratory Manual, 3rd ed.,
Sambrook, J. F., et al., Cold Spring Harbor
Laboratory Press (Cold Spring Harbor, NY: 2001),
p. A.435.

7. Molecular Cloning: A Laboratory Manual, 3rd ed.,
Sambrook, J. F., et al., Cold Spring Harbor
Laboratory Press (Cold Spring Harbor, NY: 2001),
p. A1.28.
JSX/ARO/RXR 2/04

Spermidine（胺鹽）產(chǎn)品訂購說明：
1、絕大部分產(chǎn)品備有現(xiàn)貨，一般情況下都能訂貨當(dāng)日發(fā)貨。 
2、部分非常用產(chǎn)品，需提前1－2日預(yù)訂，海外期貨則需要提前3-6周預(yù)訂。 
3、部分產(chǎn)品價(jià)格會(huì)因貨期、批次等因素發(fā)生變化，若有變動(dòng)以訂貨當(dāng)日新價(jià)格為準(zhǔn)。 
4、每日訂單截止時(shí)間為16點(diǎn)整，部分城市可到17點(diǎn)整，因超過截止時(shí)間造成當(dāng)日不能發(fā)貨的將于次日安排發(fā)貨。
5、請(qǐng)辦理完貨款后，將收據(jù)、底單等連同收貨人的地址、姓名、等以傳真、、短信、等形式通知我們。

產(chǎn)品運(yùn)輸說明：
1、極低溫產(chǎn)品：極低溫產(chǎn)品運(yùn)輸過程中加裝干冰運(yùn)輸。用干冰把產(chǎn)品包裹起來，再用泡沫盒密封，膠帶層層粘住泡沫盒，放入索萊寶的箱子，然后交付給合作快遞，安全快速高效放心的送客戶的手中，保證產(chǎn)品的性質(zhì)穩(wěn)定如一，為您的實(shí)驗(yàn)保駕護(hù)航。
2、低溫產(chǎn)品：低溫產(chǎn)品運(yùn)輸過程中加裝索萊寶冰袋運(yùn)輸。事先用冰袋把產(chǎn)品包裹起來，再使用泡沫盒密封，用膠帶嚴(yán)實(shí)密封泡沫盒，再放入索萊寶的箱子（保溫效果少可以持續(xù)一周），然后交付給合作快遞，安全快速高效放心的送客戶的手中，保證產(chǎn)品的性質(zhì)穩(wěn)定如一，為您的實(shí)驗(yàn)保駕護(hù)航。
3、常溫產(chǎn)品：常溫產(chǎn)品運(yùn)輸過程中無需加冰或者特殊包裝。產(chǎn)品由公司庫房人員快速配貨，準(zhǔn)確快速高效的快遞保證產(chǎn)品快速送達(dá)您的手中。